PANCREATIC CANCER – TUMOUR CELLS HAVE BEEN FOUND TO CHOOSE FRUCTOSE

October 1, 2012 by  
Filed under Health Blog

PANCREATIC TUMOUR CELLS CHOOSE FRUCTOSE

Glucose and fructose have long been thought of as interchangeable monosaccharide substrates with regard to metabolism. Liu and colleagues now report that fructose metabolism can result in enhanced pancreatic cancer cell proliferation by induction of thiamine-dependent transketolase flux and preferential metabolism via the nonoxidative pentose phosphate pathway to synthesize nucleic acids and increase uric acid production.

Given the global increase in refined carbohydrate consumption, recognition of this important pathway may hold significance for cancer patients, whereby reducing dietary refined fructose consumption could lead to increased survival.

Liu H, Huang D, McArthur DL, et al. Fructose induces transketolase flux to promote pancreatic cancer growth Cancer Res 2010;70:6368–76.

FURTHER RESEARCH SHOWING THE LINK BETWEEN SUGAR INTAKE AND CANCER CAN BE FOUND HERE:

Sugars (particularly fructose, given its abundance in the modern diet) must be considered with reference to cancer cell metabolism. Cancer cells utilize similar sugars in distinct ways, which may present important new therapeutic avenues of targeting cancer. To read more on this research click here: http://www.ncbi.nlm.nih.gov/pubmed/21623683

 

Yours In Great Health,

Sar Rooney BHSc., ND., DC., DASc., GDSc. (Hons), MATMS, MNHAA, MHATO

Naturopathic Medicine Practitioner, Lecturer, Researcher

 

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Sar Rooney is a Naturopathic Medicine Practitioner specialising in Anxiety and Depression |Women’s Health| Hormonal Imbalances | Thyroid Disorders | Digestive Health | Genetic Polymorphisms (MTHFR/Pyroluria) | Nutritional Medicine | Optimal Wellness & Disease Prevention 

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