TAKING ANTIOXIDANTS MAY HELP PREVENT SKIN CANCER
May 30, 2013 by admin
Filed under Health Blog
NATURAL PHENOLICS IN THE PREVENTION OF UV-INDUCED SKIN DAMAGE. A REVIEW
UV skin exposure induces extensive generation of reactive oxygen species (ROS). These can react with DNA, proteins, fatty acids and saccharides causing oxidative damage. Such injuries result in a number of harmful effects: disturbed cell metabolism, morphological and ultrastructural changes, attack on the regulation pathways and, alterations in the differentiation, proliferation and apoptosis of skin cells.
These processes can lead to photoaging and skin cancer development. One approach to protecting human skin against the harmful effects of UV irradiation is to use antioxidants as photoprotectives. In recent years naturally occurring herbal compounds such as phenolic acids, flavonoids, and high molecular weight polyphenols have gained considerable attention as beneficial protective agents.
Human skin is constantly exposed to the UV irradiation present in sunlight. This may induce a number of pathobiological cellular changes. The development of novel preventive and therapeutic strategies depends on our understanding of the molecular mechanism of UV-damage. Plant phenolics are one candidate for prevention of the adverse effects of UV radiation on the skin.
Yours In Great Health, Sar Rooney BHSc., ND., DC., DASc., GDSc. (Hons), MATMS, MNHAA, MHATO Naturopathic Medicine Practitioner, Lecturer, Researcher Earth Medicine TM Web: www.EarthMedicine.com Email: [email protected] Facebook: http://www.facebook.com/EarthMedicineHealth
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Source: Alena Svobodová, Jitka Psotová, Daniela Walterová. Biomed. Papers 147(2), 137–145 (2003).
